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The purpose of this module is to introduce the concept of collective impact as a model and method for designing data driven collective impact initiatives. The principles and phases of collective impact are described and explained. Collective impact thinking requires a shift in mind that requires attention to systems thinking. Using a collective impact mindset supports and encourages collaboration and team science and the use of standardized data sets to understand and support knowledge work and translation with community and population data sets. Example case studies illustrate the power and potential of collective impact efforts to create transformational changes to support desired health care futures.