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Older adults are more likely to consume more prescription and non-prescription medications, and this can place them at high risk for unintended harmful effects. An important component of the care of older adults relates to medication management. This course offers healthcare professionals and learners a comprehensive understanding of the physiological changes that occur with aging and their implications on medication management. It aims to equip participants with essential knowledge and skills to ensure safe and appropriate prescribing for older adults. Through a series of engaging presentations, attendees will explore key concepts in pharmacology, evidence-based frameworks, and interdisciplinary practical strategies to optimize prescribing practices and enhance patient care across the continuum of care sites. This introductory module will introduce the Geriatric 5Ms framework and then discuss the basic science concepts of pharmacokinetics and pharmacodynamics as it relates to medication management in older adults. It will emphasize the importance of calculating accurate renal function in older adults and explore the reasoning behind the prescribing mantra 鈥淪tart Low and Go Slow鈥� in older people. It will highlight the special considerations of medication prescribing in older adults with certain geriatric syndromes like frailty, dementia and multimorbidity.