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Back to Whole genome sequencing of bacterial genomes - tools and applications

Learner Reviews & Feedback for Whole genome sequencing of bacterial genomes - tools and applications by Technical University of Denmark (DTU)

4.6
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1,609 ratings

About the Course

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

Top reviews

AR

May 19, 2023

Excellent course for students who don't know much about sequencing and its analysis. It's very easy and very understandable for students new to bioinformatics.

MO

Jan 3, 2025

The course is very educative, and I enjoyed the presentations. However, I found that I could not use most of the tools. It seems the web-based versions have been discontinued.

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201 - 225 of 420 Reviews for Whole genome sequencing of bacterial genomes - tools and applications

By Vedant G

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Sep 4, 2020

Excellent course and gained very useful knowledge from tutors

By CHANCHALA A

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Jul 3, 2020

Feeling happy to learn all these courses for my future scope

By Hassan A

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Jun 12, 2019

The Design, of course, is best as per researcher requirement.

By Abdallh F A D

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Aug 23, 2022

vary helpful and get started for new school of microbiology

By Suramya S

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Jul 18, 2022

I thoroughly enjoyed this course and learned a lot as well.

By Adil M

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Jul 1, 2019

It was highly informative and interesting. I enjoyed alot

By Sufiyan M

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Jul 27, 2021

It was much informative and well prepared and conceptual

By Nagwan G E M

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Aug 27, 2020

very useful and intersting course I finshed it in 4 days

By Ratih R

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Mar 3, 2025

Very easy to understand and to apply. Thank you so much

By Sylvia D

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Jan 17, 2021

very useful bioinformatics course with hand on training

By Marc B F

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May 2, 2018

The tools provided are very interesting and easy to use

By Victoria N

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May 16, 2023

So grateful for the knowledge that I needed so badly.

By Pink S

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Mar 25, 2023

Very informative course for healthcare biotechnology.

By 劉時詠[Alex]

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Dec 17, 2021

prefect class, with proper training for the students

By julio a a j

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Mar 16, 2018

excelente curso me sirvió mucho para mi phD, gracias!

By Aritra B

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May 6, 2023

The course was highly informative and comprehensive.

By Emmanuel K

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Mar 29, 2024

Very good teaching and easy to comprehend. Thanks

By Blanchard B

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May 9, 2022

All I expected to learn by following this course.

By Toyin A A

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Sep 4, 2019

Its quite interesting and technical. i enjoyed it

By LOAI A S

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Nov 11, 2024

Giving me excellent information about WGS tools.

By Aneezay J

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Jul 18, 2022

It is very brilliant experience in coursera.

By Mohamed H A E

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Apr 19, 2020

I'm so happy for being one of your learners..

By Eloy H

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Oct 28, 2018

It's a great course and it's not so difficult

By Dhanashree J A

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Nov 21, 2020

Very well explained and interesting course.

By Zuzana K

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Feb 26, 2020

Great course, I found it extremely helpful.